UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to ITGA1

COL1A1 — ITGA1

Pathways - manually collected, often from reviews:

KEGG Focal adhesion: CHAD/COL11A1/COL11A2/COL1A1/COL1A2/COL2A1/COL3A1/COL4A1/COL4A2/COL4A4/COL4A5/COL4A6/COL5A1/COL5A2/COL5A3/COL6A1/COL6A2/COL6A3/COL6A6/COMP/FN1/IBSP/LAMA1/LAMA2/LAMA3/LAMA4/LAMA5/LAMB1/LAMB2/LAMB3/LAMB4/LAMC1/LAMC2/LAMC3/RELN/SPP1/THBS1/THBS2/THBS3/THBS4/TNC/TNN/TNR/TNXB/VTN/VWF → Complex of 21 proteins (protein-protein, activation)
KEGG ECM-receptor interaction: COL11A1/COL11A2/COL1A1/COL1A2/COL2A1/COL3A1/COL4A1/COL4A2/COL4A4/COL4A5/COL4A6/COL5A1/COL5A2/COL5A3/COL6A1/COL6A2/COL6A3/COL6A6 → Complex of ITGA1-ITGB1 (protein-protein, activation)
NCI Pathway Database VEGFR3 signaling in lymphatic endothelium: alpha1/beta1 Integrin/Type I Collagen complex (ITGA1-ITGB1-COL1A1-COL1A2) → VEGFR3/VEGFD complex (FLT4-FIGF) (modification, collaborate)
Wang et al., J Biol Chem 2001
Evidence: mutant phenotype, assay
NCI Pathway Database VEGFR3 signaling in lymphatic endothelium: alpha1/beta1 Integrin/Type I Collagen complex (ITGA1-ITGB1-COL1A1-COL1A2) → VEGFR3/VEGFD/Type I Collagen/alpha1/beta1 Integrin complex (FIGF-FLT4-COL1A1-COL1A2-ITGA1-ITGB1) (modification, collaborate)
Wang et al., J Biol Chem 2001
Evidence: mutant phenotype, assay
NCI Pathway Database VEGFR3 signaling in lymphatic endothelium: VEGFR3/VEGFD complex (FLT4-FIGF) → VEGFR3/VEGFD/Type I Collagen/alpha1/beta1 Integrin complex (FIGF-FLT4-COL1A1-COL1A2-ITGA1-ITGB1) (modification, collaborate)
Wang et al., J Biol Chem 2001
Evidence: mutant phenotype, assay
NCI Pathway Database Beta1 integrin cell surface interactions: alpha1/beta1 Integrin/Type I Collagen complex (ITGA1-ITGB1-COL1A1-COL1A2) → Type I Collagen complex (COL1A1-COL1A2) (modification, collaborate)
Tomaselli et al., Neuron 1990, Kramer et al., J Biol Chem 1989, Luque et al., FEBS Lett 1994 *, Pfaff et al., Exp Cell Res 1993, Calderwood et al., J Biol Chem 1997
Evidence: physical interaction
NCI Pathway Database Beta1 integrin cell surface interactions: alpha1/beta1 Integrin/Type I Collagen complex (ITGA1-ITGB1-COL1A1-COL1A2) → alpha1/beta1 Integrin complex (ITGA1-ITGB1) (modification, collaborate)
Tomaselli et al., Neuron 1990, Kramer et al., J Biol Chem 1989, Luque et al., FEBS Lett 1994 *, Pfaff et al., Exp Cell Res 1993, Calderwood et al., J Biol Chem 1997
Evidence: physical interaction
NCI Pathway Database Beta1 integrin cell surface interactions: Type I Collagen complex (COL1A1-COL1A2) → alpha1/beta1 Integrin complex (ITGA1-ITGB1) (modification, collaborate)
Tomaselli et al., Neuron 1990, Kramer et al., J Biol Chem 1989, Luque et al., FEBS Lett 1994 *, Pfaff et al., Exp Cell Res 1993, Calderwood et al., J Biol Chem 1997
Evidence: physical interaction
NCI Pathway Database VEGFR3 signaling in lymphatic endothelium: VEGFR3/Type I Collagen/alpha1/beta1 Integrin complex (FLT4-COL1A1-COL1A2-ITGA1-ITGB1) → alpha1/beta1 Integrin/Type I Collagen complex (ITGA1-ITGB1-COL1A1-COL1A2) (modification, collaborate)
Wang et al., J Biol Chem 2001
Evidence: physical interaction
NCI Pathway Database VEGFR3 signaling in lymphatic endothelium: VEGFR3/Type I Collagen/alpha1/beta1 Integrin complex (FLT4-COL1A1-COL1A2-ITGA1-ITGB1) → VEGFR3 (FLT4) (modification, collaborate) Wang et al., J Biol Chem 2001
Evidence: physical interaction
NCI Pathway Database VEGFR3 signaling in lymphatic endothelium: alpha1/beta1 Integrin/Type I Collagen complex (ITGA1-ITGB1-COL1A1-COL1A2) → VEGFR3 (FLT4) (modification, collaborate) Wang et al., J Biol Chem 2001
Evidence: physical interaction