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IL6 — NPY4R
Text-mined interactions from Literome
Salinthone et al., Am J Physiol Gastrointest Liver Physiol 2004
(Inflammation) :
Expression of IL-1beta,
IL-6 , IL-8, and COX-2 mRNA was
reduced by 30 microM
PP1 , an Src family tyrosine kinase inhibitor, and by 25 microM SB-203580, a p38 MAPK inhibitor
Gruber et al., Cell reports 2013
(Liver Neoplasms, Experimental...) :
Consequently,
IL-6Ra deficiency
activates PP-1a and Mule expression, resulting in increased Mcl-1 turnover and protection against HCC development