Jin et al., J Clin Invest 1995
(Hypotension...) :
BPI treated immediately after LPS reduced the circulating levels of endotoxin and IL-6 but increased the circulating levels of TNF
Arditi et al., Infect Immun 1994
:
BPI also inhibited LPS induced tumor necrosis factor alpha, IL-1 beta, and IL-6 release from human whole blood
Dentener et al., J Immunol 1993
:
LBP was shown to enhance LPS induced TNF-alpha, IL-6 , and IL-8 release by mononuclear phagocytic cells, whereas BPI inhibited the release of these cytokines