Gene interactions and pathways from curated databases and text-mining

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HNRNPH1 — NANOG

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: HNRNPH1 → NANOG (decreases)
    Evidence: FROM TEXT and Figure 6: Hybridization to the U133A DNA microarray, Genes downregulated in NANOG cells compared with both 2-day-old EBs and wild-type ES cells. These genes may also be targets of NANOG, which has been suggested to be both a transcriptional activator and repressor. In addition, genes reported to be upregulated upon knock-down of Nanog in MESCs (Mitsui et al., 2003) are downregulated upon overexpression of NANOG in HESCs. These include parietal endoderm markers (like LAMB1, downregu...