◀ Back to FAS
FAS — PTPN13
Pathways - manually collected, often from reviews:
-
BioCarta fas signaling pathway (cd95):
FAS/DAXX/FADD/Caspase 10/FAS L complex (FAS-DAXX-FADD-CASP10-FASLG)
→
PTPN13
(modification, collaborate)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Hprd Interaction:
FAS
—
PTPN13
(in vivo)
Ivanov et al., Mol Cell Biol 2003*, Sato et al., Science 1995*, Yanagisawa et al., J Biol Chem 1997*, Ekiel et al., J Biomol NMR 1998*
-
IRef Hprd Interaction:
FAS
—
PTPN13
(two hybrid)
Ivanov et al., Mol Cell Biol 2003*, Sato et al., Science 1995*, Yanagisawa et al., J Biol Chem 1997*, Ekiel et al., J Biomol NMR 1998*
-
IRef Hprd Interaction:
FAS
—
PTPN13
(in vitro)
Ivanov et al., Mol Cell Biol 2003*, Sato et al., Science 1995*, Yanagisawa et al., J Biol Chem 1997*, Ekiel et al., J Biomol NMR 1998*
-
IRef Intact Interaction:
PTPN13
—
FAS
(physical association, anti bait coimmunoprecipitation)
Li et al., Int J Cancer 2000*
-
IRef Intact Interaction:
PTPN13
—
FAS
(physical association, anti tag coimmunoprecipitation)
Ivanov et al., Mol Cell Biol 2003*
-
IRef Ophid Interaction:
PTPN13
—
FAS
(aggregation, confirmational text mining)
Yanagisawa et al., J Biol Chem 1997*
-
IRef Ophid Interaction:
PTPN13
—
FAS
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Bompard et al., J Biol Chem 2002
(Breast Neoplasms) :
These results provide the first evidence that
PTPL1/FAP-1 has a key role in the apoptotic process in human breast cancer cells
independent of
Fas but associated with an early inhibition of the insulin receptor substrate-1/phosphatidylinositol 3-kinase pathway
Ivanov et al., Mol Cell Biol 2003
:
Forced expression of
FAP-1 reduces cell surface
Fas levels and increases the intracellular pool of Fas within the cytoskeleton network
Ivanov et al., J Biol Chem 2006
(Melanoma) :
Using TIG3 normal human fibroblasts and human melanoma cell lines, we investigated transcriptional regulation of
FAP-1 , a
regulator of
Fas translocation in the cell