Gene interactions and pathways from curated databases and text-mining

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CCND1 — GAST

Text-mined interactions from Literome

Pradeep et al., Oncogene 2004 (Stomach Neoplasms) : Gastrin mediated activation of cyclin D1 transcription involves beta-catenin and CREB pathways in gastric cancer cells ... Since mature, amidated gastrin ( G-17 ) can induce cyclin D1 , we determined whether G-17 mediated induction of cyclin D1 transcription involved Wnt signaling and CRE binding protein ( CREB ) pathways
Steigedal et al., Am J Physiol Gastrointest Liver Physiol 2007 : Inducible cAMP early repressor suppresses gastrin mediated activation of cyclin D1 and c-fos gene expression ... Here we show that gastrin induces transcription of cell cycle gene cyclin D1 and protooncogene c-fos in the neuroendocrine pancreatic cell line AR42J and that this gastrin response is inhibited by endogenous inducible cAMP early repressor (ICER)