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CASP7 — FOS
Text-mined interactions from Literome
Siegmund et al., J Biol Chem 2001
:
FasL- and TRAIL mediated up-regulation of
c-Fos was completely
dependent on the presence of Fas associated death domain protein ( FADD ) and
caspase-8 , but caspase activity seemed to be dispensable as a pan inhibitor of caspases had no inhibitory effect
Romashko et al., Free Radic Biol Med 2003
(Hyperoxia...) :
Interestingly, hydrogen peroxide induced oxidative apoptosis of MLE-12 cells, with a shrinking nuclear morphology and activated
caspase-3 activity, is also
mediated by
AP-1 , JNK, and p38
Yip et al., J Bone Miner Res 2005
(Calcium Signaling) :
In this study, we showed a biphasic effect of TG on osteoclast formation and apoptosis through the regulation of ROS production,
caspase-3 activity, cytosolic Ca2+, and RANKL induced
activation of NF-kappaB and
AP-1 activities
Oh et al., J Biomed Sci 2007
:
HeLa cells treated with phytoglycoprotein ( 150 kDa ) were killed by
activation of
caspase 3 via inhibitory activities of NF-kappaB and
AP-1
Yang et al., Neurol Res 2007
(Cerebral Hemorrhage) :
Acupunctural treatment, especially at the ST36 acupoint, suppressed the intracerebral hemorrhage induced
caspase3 expression in the stratum, and it also
inhibited expression of
Fos and cell proliferation in the dentate gyrus
Zhou et al., Cell Prolif 2007
(MAP Kinase Signaling System) :
More importantly, under both stress conditions, overexpression of JunD alone or overexpression of both
c-Fos and JunD
reduced caspase 3 activity and cell death
Ballaun et al., Biochem Biophys Res Commun 2008
:
Transcription of the
caspase-14 gene in human epidermal keratinocytes
requires AP-1 and NFkappaB ... Our data reveal the basic organization of the human caspase-14 promoter and suggest an important
role of
AP-1 and NFkappaB in the transcriptional control of
caspase-14
Hasegawa et al., J Immunol 2009
:
ASC mediated
AP-1 activation was
inhibited by chemical or protein inhibitors for caspase-8, caspase-8 targeting small interfering RNA, and p38 and JNK inhibitors, but not by a caspase-1 inhibitor,
caspase-9 or Fas associated death domain protein ( FADD ) dominant negative mutants, FADD- or RICK targeting small interfering RNAs, or a MEK inhibitor, indicating that the ASC induced AP-1 activation is mediated by caspase-8, p38, and JNK, but does not require caspase-1, caspase-9, FADD, RICK, or ERK
Henrotin et al., Osteoarthritis Cartilage 2010
(Inflammation...) :
Curcumin blocks IL-1beta induced proteoglycan degradation,
AP-1/NF-kappaB signalling, chondrocyte apoptosis and
activation of
caspase-3