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DES — TP53

Text-mined interactions from Literome

Salleh et al., Toxicology 2003 : DES induced the expression of 12 genes ( bad, bax, bcl-x, caspase-1, p53 , cyclin D3, GADD45, p21, p15, p27, p57 and Skp1 ) and down-regulated the expression of eight genes ( bcl-2, caspase-2, caspase-7, caspase-8, E124, iNOS, mdm2 and NFkappab1 ) at twofold or greater levels
Palangat et al., Int J Oncol 1996 : The DES mediated enhanced tyrosine phosphorylation of p53 coincided with increased cell proliferation of renal tubular epithelial cells of Syrian hamster