◀ Back to TLR2

IL23A — TLR2

Text-mined interactions from Literome

Re et al., J Biol Chem 2001 : TLR2 stimulation also resulted in preferential induction of IL-8 and p19/IL-23
Yang et al., Cell Microbiol 2006 (MAP Kinase Signaling System) : To extend these studies, we examined the nature of the involvement of toll-like receptors ( TLRs ) and intracellular signalling pathways downstream from PI3K in M. tbc induced IL-23 expression in human MDMs. M. tbc induced Akt activation and IL-23 expression were essentially dependent on TLR2
Carmody et al., J Immunol 2007 : Essential roles of c-Rel in TLR induced IL-23 p19 gene expression in dendritic cells
Karrasch et al., J Immunol 2007 (Colitis...) : IL-10-/- ; MyD88-/- mice were used to assess E. faecalis/E. coli induced TLR dependent signaling and IL-23 gene expression
van Beelen et al., Immunity 2007 (Bacterial Infections...) : MDP enhanced obligate bacterial Toll-like receptor ( TLR ) agonist induction of IL-23 and IL-1, which promoted IL-17 expression in T cells
Weaver et al., Eur J Immunol 2010 : Stimulation of C5aR ( -/- ) DC with OVA and TLR2 ligand Pam ( 3 ) CSK ( 4 ) increased TGF-beta production and induced high levels of IL-6 and IL-23 but only minor amounts of IL-12 leading to differentiation of Th cells producing IL-17A and IL-21
Hayashi et al., Immunology 2010 : In the present study, we examined the effect of prostaglandin E ( 2 ) ( PGE ( 2 ) ) treatment of DCs during differentiation on IL-12 and IL-23 production in response to Toll-like receptor ( TLR ) stimulation
Goodall et al., Proc Natl Acad Sci U S A 2010 (Chlamydia Infections) : Knockdown of CHOP in U937 cells significantly reduced the synergistic effects of TLR and ER stress on IL-23p19 expression, but did not affect expression of other LPS-responsive genes
Ather et al., J Immunol 2011 (Disease Models, Animal...) : Furthermore, SAA drives production of IL-1a, IL-1ß, IL-6, IL-23 , and PGE ( 2 ), causes dendritic cell ( DC ) maturation, and requires TLR2 , MyD88, and the NLRP3 inflammasome for secretion of IL-1ß by DCs and macrophages
Dejima et al., Infect Immun 2011 (Candidiasis) : Early IL-23 production in a TLR2/MyD88 dependent manner and IL-23 triggered tyrosine kinase 2 (Tyk2) signaling were essential for IL-17A production by ?d T cells
Kwok et al., Arthritis Res Ther 2012 (Sjogren's Syndrome) : TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren 's syndrome ... The stimulation of TLR2, TLR4 and TLR6 additively induced the production of IL-17 and IL-23 from the PBMCs of pSS patients especially in the presence of TLR2 stimulation ... The stimulation of TLR2 , TLR4 and TLR6 additively induced the production of IL-17 and IL-23 from the PBMCs of pSS patients especially in the presence of TLR2 stimulation ... Our data demonstrate that TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in pSS
Zaal et al., Immunobiology 2013 : While C5a indeed enhanced cytokine production of immature DCs, the addition of C5a inhibited production of IL-12, IL-23 and TNFa induced by various TLR ligands such as LPS, R848 and Pam ( 3 ) CSK ( 4 )
den Dunnen et al., Blood 2012 (Bacterial Infections...) : First, TLR-Fc?RIIa costimulation strongly increased transcription of pro-IL-1ß and IL-23p19
DePaolo et al., J Exp Med 2012 (Inflammation...) : Furthermore, induction of T ( H ) 17 immunity during oral infection is dependent on TLR1 and results from the combinatorial effect of TLR2/TLR1 induced IL-6 and IL-23 and the presence of TGF-ß in the intestinal environment
McBerry et al., J Immunol 2012 (Disease Models, Animal...) : p38 MAPK activation and IL-12p70 production was more robust from TFF2 ( -/- ) CD8+ DC compared with WT CD8+ DC and treatment of WT DC with rTFF2 suppressed TLR induced IL-12/23p40 production
Perugorria et al., Hepatology 2013 (Liver Cirrhosis...) : KCs lacking Tpl2 display defects with TLR induction of cytokines interleukin (IL)-1ß, IL-10, and IL-23
Compté et al., PloS one 2013 : The aim of our study was to define the relative contribution of age and clinical status on TLR induced interleukin (IL)-12p70 and IL-23 production as these cytokines play an important role in the protection against intracellular and extracellular pathogens, respectively
Callahan et al., J Immunol 2013 (Disease Susceptibility...) : ABIN-1-deficient DCs display exaggerated NF-?B and MAPK signaling and produce more IL-23 than do normal cells in response to TLR ligands
Rizzo et al., Int Immunopharmacol 2013 : Pre-treatment with the anti-TLR2/4 antibody abolished the inhibitory effects of L. plantarum on IL-17 and IL-23 production following S. pyogenes infection, indicating that L. plantarum downregulates TLR2/4 dependent IL-17 and IL-23 production
Ma et al., PloS one 2013 : In this study, our data suggest that Tim-3 and IL-12/IL-23 gene transcriptions are regulated by enhanced or silenced Gal-9 expression within monocytes through synergizing with TLR signaling