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KRAS — RHOA

Pathways - manually collected, often from reviews:

• NCI Pathway Database Plasma membrane estrogen receptor signaling: RHOA/GDP complex (RHOA) → RAS family/GTP complex (HRAS_KRAS_HRAS_KRAS_NRAS) (modification, collaborate)
  Simoncini et al., Mol Endocrinol 2006
  Evidence: mutant phenotype

Text-mined interactions from Literome

Dreissigacker et al., Cell Signal 2006 (Neoplasm Invasiveness...) : Stable expression of EGFP-K-Ras ( V12 ) down-regulated the activity of Rac1 and RhoA , resulting in reduced subcortical actin filaments and stress fibers, which might contribute to the epithelial dedifferentiation
Basu Roy et al., Int J Cancer 2013 (Cell Transformation, Neoplastic...) : This increased migration is highly dependent on the RhoA GTPase, indicating that an activated K-RAS modulates migration in part via caveolin-1 induction, and increasing RhoA activity via phospho-caveolin-1