Matsubara et al., Oncogene 1999
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These results indicate that Ras recruits RalGDS to the plasma membrane and that the translocated RalGDS induces the activation of Ral, but that Rap1 does not activate Ral due to distinct subcellular localization
Linnemann et al., J Biol Chem 2002
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Furthermore, it is shown that Rap1 , which was originally identified as a Ras antagonist, can block Ras mediated RalGDS signaling only when RalGDS contains an intact RBD