UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to NOTCH1

NOTCH1 — SNAI1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: SNAI1 — NOTCH1 (physical association, affinity chromatography technology) Lim et al., BMC biology 2011 *
IRef Biogrid Interaction: SNAI1 — NOTCH1 (direct interaction, pull down) Lim et al., BMC biology 2011 *

Text-mined interactions from Literome

Katoh et al., Int J Mol Med 2008 : Hedgehog signals induce JAG2 upregulation for Notch-CSL mediated SNAI1 upregulation, and also induce TGFbeta1 secretion for ZEB1 and ZEB2 upregulation via TGFbeta receptor and NF-kappaB
Volckaert et al., J Clin Invest 2011 (Lung Injury...) : After naphthalene injury, PSMCs secreted Fgf10 to activate Notch signaling and induce Snai1 expression in surviving variant Clara cells, which subsequently underwent a transient epithelial to mesenchymal transition to initiate the repair process