Gene interactions and pathways from curated databases and text-mining

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CCNE1 — MYLIP

Text-mined interactions from Literome

Zhu et al., Nucleic Acids Res 2012 (Neoplasms) : Further investigation disclosed that miR-26a/b directly suppressed the expression of CDK6 and cyclin E1 , which resulted in reduced phosphorylation of pRb
Akama et al., Mol Endocrinol 2012 : These results suggest that TSH activates cAMP/protein kinase A and PI3K cascades to decrease miR-16 and miR-195 , which induce Mapk8, Ccne1 , and Cdc6 to activate cell proliferation
Furuta et al., PloS one 2013 (Carcinoma, Hepatocellular...) : Among the candidates, we successfully identified CCNE1 , CDC25A, CCND3, CDK4, and BTRC as direct targets for miR-497 and miR-195