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IRAK3 — MAP3K7

Text-mined interactions from Literome

Takaesu et al., Mol Cell Biol 2001 (MAP Kinase Signaling System) : In this report, we investigate the role of IRAK in the activation of TAK1 ... Genetic analysis reveals that IRAK is required for IL-1 induced activation of TAK1
Qian et al., J Biol Chem 2001 : Our results show that IRAK is required for the IL-1 induced phosphorylation of TAK1 , TAB1, and TAB2
Xiao et al., J Biol Chem 2008 : Importantly, the negative impact of Pellino 3b on IL-1 induced IRAK degradation correlated with the inhibitory effect of Pellino 3b on the IL-1 induced TAK1 dependent pathway, suggesting that a positive role of IRAK degradation in IL-1 induced TAK1 activation