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JUN — PLCG1
Text-mined interactions from Literome
Qu et al., Blood 2004
:
The antigen induced tyrosine phosphorylation of FcepsilonRI, Syk,
phospholipase C-gamma (PLC-gamma) ,
activation of
c-Jun N-terminal kinase (JNK) , extracellular signal regulated kinase ( ERK ), inhibitor of nuclear factor kappaB kinase ( IKK ), and Ca++ influx were all suppressed in the cells overexpressing Cbl-b in the lipid raft
Yang et al., J Biol Chem 2008
(MAP Kinase Signaling System) :
Lastly, we examined the role of the immediate-early transcription factors AP-1 and NF-kappaB and have found that
phospholipase C-gamma dependent
c-Jun and ERK dependent c-fos, but not the NF-kappaB, are strongly activated by bFGF, which in turn regulates the neuronal differentiation of BMSCs
Fu et al., J Exp Med 2010
(Autoimmune Diseases...) :
We demonstrate that
PLCgamma1 deficiency affects positive and negative selection, significantly reduces single positive thymocytes and peripheral T cells, and
impairs TCR induced proliferation and cytokine production, and the activation of ERK, JNK,
AP-1 , NFAT, and NF-kappaB