Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Alvarez et al., J Neurochem 2005 (Neuroblastoma) : Moreover, gp120 rapidly activates the c-Jun amino-terminal kinase (JNK) and p38 mitogen activated protein kinase phosphorylation
Kapasi et al., Nephron. Experimental nephrology 2006 : Furthermore, p300 and HIV-1 gp120 synergistically increase TGF-beta, ATF-2 and activating protein-1 (AP-1) expression
Jabado et al., Eur J Immunol 1994 : Interaction of HIV gp120 and anti-CD4 antibodies with the CD4 molecule on human CD4+ T cells inhibits the binding activity of NF-AT, NF-kappa B and AP-1 , three nuclear factors regulating interleukin-2 gene enhancer activity
Lannuzel et al., Ann Neurol 1997 (AIDS Dementia Complex) : Gp120 activated c-Jun N-terminal kinase (JNK) and p42 extracellular regulated kinase (ERK) in primary CNS cells, with an early peak of activation at 2 to 5 minutes that was not present when pure microglial or astrocyte cultures were tested, followed by a late and sustained activation ( 10 and 60 minutes ) in primary and enriched glial cell cultures as well as in transformed microglial cells