Gene interactions and pathways from curated databases and text-mining

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ITGAL — ITGAM

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: ITGAM — ITGAL (interaction, mapped from bind)
  • STRING interaction: ITGAL — ITGAM (interaction, mapped from reactome kegg_pathways)

Text-mined interactions from Literome

Esser et al., J Nutr 2013 (Obesity) : In both groups and after all shakes were consumed, AIX decreased ; plasma soluble intercellular adhesion molecule ( sICAM ) 1, sICAM3, soluble vascular cell adhesion molecule ( sVCAM ) 1, and interleukin-8 increased ; monocyte CD11a , CD11b, and CD621 expression increased ; neutrophil CD11a, CD11b , and CD621 expression increased ; and lymphocyte CD62l expression increased ( P < 0.05 )
Darcissac et al., Cell Immunol 1996 : Whereas CD11a was increased only on monocytes, CD11b , CD11c, and CD18 were strongly enhanced on monocytes and polymorphonuclear cells ( PMNs ) after treatment with MDPs
Plusa et al., Gut 1996 (Cholestasis) : The basal expression of L-selectin, CD11a , and CD15 was significantly decreased in jaundiced patients ( p < 0.05 ) and the expression of CD11b in response to stimulation with fMLP and endotoxin was significantly impaired in the jaundiced group
Buysmann et al., J Lab Clin Med 1997 (Lymphopenia) : In vitro, both immunoglobulin A and immunoglobulin G2a CD3 mAbs induce immediate activation of CD11a/CD18 , with concomitant up-regulation of CD11b/CD18 on T cells, each of which is shown to be involved in the concurrent adhesion of T cells to endothelium