Ming et al., EMBO J 1998
:
Moreover, transfection of activated MEKK1 amplified ionomycin induced IL-3 mRNA expression at the post-transcriptional level, and a dominant negative mutant of JNK counteracted mRNA stabilization by ionomycin
Nemoto et al., Mol Cell Biol 1998
:
MEKK1 is activated by tumor necrosis factor alpha (TNF-alpha) and interleukin-1 and can potentiate the stimulatory effect of TNF-alpha on IKK and NF-kappaB activation