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CDKN1A — IL3
Text-mined interactions from Literome
Khanna et al., J Biol Chem 2001
:
Using a C-terminal epitope-specific p21 ( WAF-1 ) antibody, v-Abl PTK mediated increase in
p21 ( WAF-1 ) could be detected in intact cells only in the
presence of
IL-3 ... The binding of CDK2, CDK4, or proliferating cell nuclear antigen to
p21 ( WAF-1 ) and its subcellular localization were unchanged in the
presence or absence of
IL-3
Muroya et al., Oncogene 1992
:
In contrast, basic fibroblast growth factor,
interleukin 6 and dibutyryl cAMP, which induce neuronal differentiation of PC12 cells, did not
stimulate the accumulation of
p21-GTP at any time point examined
Gündogdu et al., Molecular cancer 2010
:
High levels of RhoH allow the
IL3 dependent activation of STAT1
causing decreased proliferation through upregulation of
p21Cip1 and p27Kip1