Gene interactions and pathways from curated databases and text-mining

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CDKN1A — IL3

Text-mined interactions from Literome

Khanna et al., J Biol Chem 2001 : Using a C-terminal epitope-specific p21 ( WAF-1 ) antibody, v-Abl PTK mediated increase in p21 ( WAF-1 ) could be detected in intact cells only in the presence of IL-3 ... The binding of CDK2, CDK4, or proliferating cell nuclear antigen to p21 ( WAF-1 ) and its subcellular localization were unchanged in the presence or absence of IL-3
Muroya et al., Oncogene 1992 : In contrast, basic fibroblast growth factor, interleukin 6 and dibutyryl cAMP, which induce neuronal differentiation of PC12 cells, did not stimulate the accumulation of p21-GTP at any time point examined
Gündogdu et al., Molecular cancer 2010 : High levels of RhoH allow the IL3 dependent activation of STAT1 causing decreased proliferation through upregulation of p21Cip1 and p27Kip1