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EGF — MYLIP
Text-mined interactions from Literome
Adams et al., Mol Endocrinol 2009
(Breast Neoplasms) :
The
role of
miR-206 in the
epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells ... Blocking
EGF induced enhancement of
miR-206 with antagomiR-206 abrogated the EGF-inhibitory effect on ERalpha, SRC-1, and SRC-3 levels, and on estrogen response element-luciferase activity, indicating that EGFR signaling represses estrogenic responses in MCF-7 cells by enhancing miR-206 activity
Kern et al., DNA Cell Biol 2012
(Colorectal Neoplasms) :
We show that
EGF/Ras efficiently
induces the
miR-21 primary transcript, but this does not rapidly and simply translate into higher mature miR-21 levels
Jin et al., Cancer Res 2013
(Breast Neoplasms...) :
Also, we report for the first time that HER2/neu ( ERBB2 ),
EGF , and TNF-a
promote miR-23b/27b expression through the AKT/NF-?B signaling cascade