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CXCL12 — ROCK2
Text-mined interactions from Literome
Struckhoff et al., J Cell Sci 2010
:
Interestingly,
CXCL12 partially
reduces the level of
ROCK activity generated by attachment, which supports a model in which stimulation with CXCL12 regulates tumor cell adhesion events by providing an optimal level of ROCK activity for effective migration ... Interestingly,
CXCL12 partially
reduces the level of
ROCK activity generated by attachment, which supports a model in which stimulation with CXCL12 regulates tumor cell adhesion events by providing an optimal level of ROCK activity for effective migration
Rafferty et al., Cell Immunol 2012
:
Suppressing
ROCK with the Y27632 inhibitor
suppressed IL-1 stimulated Caco-2 cell
CXCL8/IL-8 and IEC-6 cell CCL2/MCP-1 secretion and mRNA levels