Herold et al., Mol Cell 2002
:
Miz-1 binds to the p21Cip1 core promoter in vivo and is required for upregulation of p21Cip1 upon UV irradiation
Jeon et al., J Biol Chem 2009
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In particular, ZBTB2 repressed transcription of the p21 gene by acting on the two distal p53 binding elements and the proximal Sp1 binding GC-box 5/6 elements
Liu et al., Oncogene 2010
(Lymphoma) :
A role of Miz-1 in Gfi-1 mediated transcriptional repression of CDKN1A Morandell et al., Virology 2012
:
Co-expression of E7 with Miz-1 inhibited Miz-1 induced p21 ( Cip1 ) expression from the minimal-promoter via Miz-1 DNA binding sites ... Co-expression of E7d79LEDLL83 did not inhibit Miz-1 induced p21 ( Cip1 ) expression ... These findings suggest that HPV-16 E7 can repress Miz-1 induced p21 ( Cip1 ) gene expression