Zhang et al., J Biol Chem 2000
:
The gut enriched Kruppel-like factor ( Kruppel-like factor 4 ) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter
Wu et al., Oncogene 2004
:
In addition, KLF2 upregulates p21WAF1/CIP1 expression
Siatecka et al., Mol Cell Biol 2010
:
EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation ... EKLF activates p21 not only by directly binding to an EKLF site within a previously characterized GC-rich region in the p21 proximal promoter but also by occupancy at a novel, phylogenetically conserved region that contains consensus CACCC core motifs located downstream from the p21 TATA box
Song et al., Biochem Biophys Res Commun 2012
(Papilloma) :
Furthermore, KLF10 dose-dependently activated p21 ( WAF1/CIP1 ) transcription, which was independent of p53 and Sp1 binding sites in p21 ( WAF1/CIP1 ) promoter