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APOC3 — PRKCA
Text-mined interactions from Literome
Kawakami et al., Circulation 2006
(Atherosclerosis) :
VLDL CIII+, LDL CIII+, or
apoCIII itself
activated PKCalpha and RhoA in THP-1 cells, which resulted in beta1-integrin activation and enhancement of THP-1 cell adhesion
Kawakami et al., Arterioscler Thromb Vasc Biol 2007
:
Among inhibitors specific to PKC activators, phosphatidylcholine-specific phospholipase C ( PC-PLC ) inhibitor D609 limited
apoCIII induced
PKC alpha activation and THP-1 cell adhesion ...
ApoCIII increased PC-PLC activity in THP-1 cells, resulting in
PKC alpha activation ... Pertussis toxin ( PTX ) inhibited
apoCIII induced PC-PLC activation and subsequent
PKC alpha activation , implicating PTX-sensitive G protein pathway