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FOS — SYK

Pathways - manually collected, often from reviews:

• NCI Pathway Database Fc-epsilon receptor I signaling in mast cells: Antigen/IgE/Fc epsilon R1/LYN/SYK complex (IGHE-SYK-LYN-MS4A2-FCER1G-FCER1A) → JUN/FOS complex (FOS-JUN) (modification, inhibits) Kawakami et al., J Immunol 2000, Hata et al., J Biol Chem 1998
  Evidence: assay, other species

Text-mined interactions from Literome

Kim et al., FEBS Lett 2012 (Atherosclerosis) : ROS mediated c-Jun NH ( 2 ) -terminal kinase ( JNK ) is also required for AP-1 activation, but Syk and PI3K regulated AP-1 activation independently of JNK
Koo et al., Cell Biol Int 2013 : MPA and Syk inhibitor attenuated TNF-a induced DNA binding activity of NF-?B and AP-1