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FOS — RAC3
Text-mined interactions from Literome
Wroblewski et al., J Cell Sci 2003
(Neoplasm Invasiveness) :
RhoA acted through activation of both NF-kappaB and AP-1, whereas
Rac activated NF-kappaB but not
AP-1
Lee et al., Oncogene 2009
:
In summary, Galpha(12) and Galpha(13) regulate the expression of the TGFbeta1 gene through an increase in
Rho/Rac dependent
AP-1 activity, implying that the G-protein coupled receptor ( GPCR ) -Galpha(12) pathway is involved in the TGFbeta1 mediated transdifferentiation process
Malliri et al., J Cell Biol 1998
:
Our data establish a novel link between
AP-1 activity and EGFR
activation of
Rac and Rho, which in turn mediate the actin cytoskeletal rearrangements required for cell motility and invasion