Dey et al., J Cell Biochem 1999
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We found that whereas IFNgamma inhibits CSF-1 stimulated c-Myc gene expression, it induces Mad1 expression
Cheng et al., J Biol Chem 1999
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Expression of c-Myc in response to colony stimulating factor-1 requires mitogen activated protein kinase kinase-1 ... Therefore, MEK1 participates in an obligate signaling pathway linking CSF-1R to c-Myc expression, but other signals from CSF-1R must cooperate with the MEK/ERK pathway to induce c-Myc expression and S phase entry in response to CSF-1 stimulation
Davis et al., Mol Cell Biol 1997
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When we transfected cells expressing CSF-1R ( Y809F ) with mPIP5K-Ibeta ( delta1-238 ), CSF-1 dependent induction of c-MYC and cyclin D1 was restored and ligand dependent cell proliferation was sustained