Pfeffer et al., J Biol Chem 2001
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Thus, we report that ODC inhibition activates the NF-kappa B transcription factor , which may mediate the altered physiological state of intestinal cells that occurs following polyamine depletion
Stachurska et al., Biochim Biophys Acta 2004
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In conclusion, these in vivo studies document significant cisplatin induced modulation of polyamine biosynthesis/degradation and up-regulation of c-Myc expression, and suggest that c-Myc transcription factor is involved in the induction of ODC in kidney injured with antifolate, but not with cisplatin