◀ Back to RELA

KISS1 — RELA

Text-mined interactions from Literome

Yan et al., J Biol Chem 2001 (Neoplasm Invasiveness) : However, NF-kappaB binding to the MMP-9 promoter required for expression of this collagenase was reduced by KiSS-1 expression
Cho et al., J Cell Biochem 2009 (Breast Neoplasms...) : However, it is unclear whether KiSS1 regulates TNFalpha induced NF-kappaB activation and further tumor cell migration ... Both KiSS1 overexpression and KP10 ( kisspeptin-10 ) stimulation inhibited TNFalpha induced NF-kappaB activity, suppressed TNFalpha induced cell migration and cell attachment to fibronectin in breast cancer cells while KP10 has little effect on cancer cell proliferation ... Therefore, our data demonstrate that KiSS1 inhibits TNFalpha induced NF-kappaB activation via downregulation of RhoA activation and suppression of breast cancer cell migration and invasion