Gene interactions and pathways from curated databases and text-mining

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PRL — SOCS2

Text-mined interactions from Literome

Dogusan et al., J Neuroimmunol 2000 (Leukemia) : In tonsillar cells, CIS expression was increased and SOCS-2 was induced by IL-1beta, IL-6, PRL and GH
Cwikel et al., Exp Hematol 2001 : However, CIS-1 was induced by PRL < IL-3 < PRL+IL-3, whereas CIS-2 expression was induced by PRL = IL-3 < PRL+IL-3
Ling et al., Endocrinology 2001 : In conclusion, our results demonstrate functional PRLRs in mouse adipocytes and suggest a role for CIS, SOCS-3, and SOCS-2 in regulating PRL signal transduction in adipose tissue
Dogusan et al., Endocrine 2003 : The CTL clone expressed conventional PRL receptor (PRLR), and PRL induced the expression of suppressor of cytokine signaling-3 ( SOCS-3 ) and increased the expression of SOCS-2 and cytokine-inducible src homology-2 containing protein ( CIS, another member of the SOCS family )