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CALM1 — PRL
Text-mined interactions from Literome
Davis et al., Trends Endocrinol Metab 1990
:
Calcium and
calmodulin regulation of
prolactin gene expression ...
Prolactin gene transcription is critically
dependent upon intracellular calcium and the calcium binding protein
calmodulin
Martin et al., J Biol Chem 1989
(Pituitary Neoplasms) :
Inhibitors of calmodulin or protein kinase C ( trifluroperazine, calmidazolium, H-7 ) failed to
inhibit Ca2+ activated
PRL release, and the required cytosolic protein could not be replaced by purified
calmodulin , calmodulin dependent protein kinase II, protein kinase C, or calpactin I
White et al., Methods Enzymol 1987
:
Since HMG 17 is associated with actively transcribed chromatin, its phosphorylation in GH3 cells might play a role in the
Ca2+-calmodulin dependent regulation of
prolactin gene expression by hormones and growth factors
White et al., J Biol Chem 1985
(Pituitary Neoplasms) :
Evidence for a
role of
calmodulin in the regulation of
prolactin gene expression
Merritt et al., Life Sci 1983
:
The possible
role of
calmodulin in the inhibition of
prolactin secretion by dopaminergic antagonists
Merritt et al., J Endocrinol 1983
:
The possible
role of
calmodulin in the control of
prolactin secretion was examined ... A number of phenothiazines showed a close correlation of potencies in the two systems, as did the more specific calmodulin antagonist, N- ( 6-aminohexyl ) -5-chloro-1-naphthalene sulphonamide ( W7 ), suggesting that
calmodulin may be
involved in the control of
prolactin secretion