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IRS1 — PIK3CD

Pathways - manually collected, often from reviews:

• KEGG Neurotrophin signaling pathway: IRS1/IRS2/IRS4 → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, activation)
  
• KEGG Insulin signaling pathway: IRS1/IRS2/IRS4 → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, activation)
  
• KEGG Type II diabetes mellitus: IRS1 → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, activation)
  
• KEGG Type II diabetes mellitus: IRS1/IRS2/IRS4 → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, activation)
  
• KEGG Aldosterone-regulated sodium reabsorption: IRS1/IRS2/IRS4 → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, activation)
  
• WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway: IRS1/IRS4/IRS2 → PIK3CA/PIK3R1/PIK3IP1/PIK3R2/PIK3CB/PIK3CD/PIK3R4 (activation)
  
• WikiPathways Insulin Signaling: PIK3CD/PIK3C3/PIK3R3/PIK3R1/PIK3C2G/PIK3R2/PIK3CG/PIK3CB/PIK3R4/PIK3C2A/PIK3CA → Complex of IRS1-PIK3CA (activation)
• WikiPathways Signaling Pathways in Glioblastoma: IRS1 → Complex of PIK3R1-PIK3R2-PIK3CA-PIK3CB-PIK3CD (mim-stimulation)
  
• WikiPathways DNA Damage Response (only ATM dependent): IRS1 → PIK3CA/PIK3CB/PIK3CG/PIK3CD/PIK3R1/PIK3R2/PIK3R3/PIK3R4/PIK3R5/PIK3C2A/PIK3C2B/PIK3C2G/PIK3C3 (activation)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• STRING interaction: IRS1 — PIK3CD (interaction, mapped from grid)
• STRING interaction: PIK3CD — IRS1 (interaction, mapped from bind reactome)