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PARP1 — YWHAB

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 306 proteins (association, pull down) Komarova et al., Mol Cell Proteomics 2011
• IRef Intact Interaction: Complex of 103 proteins (association, anti tag coimmunoprecipitation) Yang et al., J Proteome Res 2010
• IRef Intact Interaction: Complex of 83 proteins (association, anti tag coimmunoprecipitation) Sumara et al., Cell 2009

Text-mined interactions from Literome

Carey et al., J Biol Chem 2003 : In contrast to Raf-1, B-Raf is activated by Rap1
Dillon et al., J Biol Chem 2003 : Recent studies suggest that Rap1 can activate the MAP kinase kinase kinase B-Raf that is either endogenously or ectopically expressed
Calipel et al., J Biol Chem 2006 (Cell Transformation, Neoplastic...) : This ruled out a role for Rap1 in the PKA mediated B-Raf/ERK activation in ( WT ) B-Raf cells
Wang et al., Mol Cell Biol 2006 : Rap1 activation by Epac-CAAX, but not wild-type Epac, triggers its association with B-Raf
Ohtsuka et al., J Biol Chem 1996 : Here we have used this assay system and examined the effect of Rap1 on the B-Raf activity to phosphorylate recombinant MAP kinase kinase ( MEK )
Vossler et al., Cell 1997 : These cell type-specific actions of cAMP require the expression of the serine/threonine kinase B-Raf and activation of the small G protein Rap1