Gene interactions and pathways from curated databases and text-mining

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CCND1 — NUP43

Text-mined interactions from Literome

Terada et al., Kidney Int 1999 : In contrast, overexpression of the active form of p42/44 MAPK-activator, MKK1, increased cyclin D1 and A promoter activity and protein levels
Friedrichsen et al., J Endocrinol 2006 : We conclude that incretin induced beta-cell replication is dependent on cAMP/PKA, p42 MAPK and PI3K activities, which may involve transcriptional induction of cyclin D1
Lavoie et al., J Biol Chem 1996 : We found that inhibition of the p42/p44(MAPK) signaling by expression of dominant negative forms of either mitogen activated protein kinase kinase 1 ( MKK1 ) or p44(MAPK), or by expression of the MAP kinase phosphatase, MKP-1, strongly inhibited expression of a reporter gene driven by the human cyclin D1 promoter as well as the endogenous cyclin D1 protein