Gene interactions and pathways from curated databases and text-mining

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NOS3 — PGF

Text-mined interactions from Literome

Shirasuna et al., J Reprod Dev 2010 : In the vasoactive factors, PGF ( 2alpha ) stimulated the mRNA expressions of endothelin-1, angiotensin converting enzyme, endothelial nitric oxide synthase (NOS) and inducible NOS in the periphery area of the mid CL, but not in the early CL
Qi et al., Proc Natl Acad Sci U S A 2013 : We report here that tumor necrosis factor superfamily 15 ( TNFSF15 ) ( also known as VEGI or TL1A ), an endothelial cell secreted cytokine, simultaneously promotes mFlt1 degradation and up-regulates sFlt1 expression in EPC, giving rise to disruption of VEGF- or PlGF induced activation of eNOS and MAPK p38 and effective inhibition of VEGF-driven, EPC supported vasculogenesis in a murine Matrigel implant model