Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Kato et al., Biochem Biophys Res Commun 2003 (MAP Kinase Signaling System) : As evidenced by Western blot analysis, amphiregulin stimulated the phosphorylation of p42/p44-mitogen activated protein kinase ( MAPK ), p38-MAPK, c-Jun NH2-terminal protein kinase (JNK) , and Akt/protein kinase B (PKB), respectively
Aguiari et al., J Mol Med (Berl) 2012 (Polycystic Kidney, Autosomal Dominant) : We now show by microarray analysis, luciferase assay, mutagenesis, and chromatin immunoprecipitation that CREB and AP1 contribute to increased expression of the amphiregulin gene, which codifies for an epidermal growth factor-like peptide, in ADPKD cystic cells, thereby promoting their cell growth