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HES1 — IL8
Text-mined interactions from Literome
Lv et al., Acta Anaesthesiol Scand 2005
:
HES significantly
reduced the increased hepatic levels of TNF-alpha, IL-1beta, IL-6,
IL-8 and the mRNAs in the endotoxemic rats
Lv et al., J Int Med Res 2005
(Endotoxemia...) :
HES significantly
reduced the LPS induced increase in intestinal levels of TNF-alpha, IL-1beta, IL-6,
IL-8 and their corresponding mRNAs
Yeh et al., Life Sci 2007
(Edema...) :
In vitro,
HES suppressed the expression of
IL-8 on A549 cells and THP-1 cells, the expression of TNF-alpha, IL-1 beta, and IL-6 on THP-1 cells, the expression of ICAM-1 and VCAM-1 on A549 cells which effect cell adhesion function
Al Haj Zen et al., Circ Res 2010
(Disease Models, Animal...) :
In cultured human monocytes, Dll4 induces the transcription of Notch target gene
Hes-1 and
inhibits the basal and tumor necrosis factor-alpha stimulated production of
interleukin-8 , the human functional homolog of murine CXCL1