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IL1A — NOX1

Text-mined interactions from Literome

Katsuyama et al., Endocrinology 1999 : Both interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha potently stimulated nitrite/nitrate ( NOx ) production with a concomitant expression of iNOS mRNA and protein as demonstrated by Northern and Western blot analysis, respectively
Tojo et al., J Hypertens 2005 (Hypertension, Renal) : Nicotinamide adenine dinucleotide phosphate ( NAD ( P ) H ) oxidase is regulated by angiotensin II, interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha via p38 mitogen activated protein kinase ( MAPK )
Moe et al., J Cell Mol Med 2011 (Ventricular Remodeling) : Nox2 and Nox4 siRNA significantly attenuated TNF-a induced ROS and upregulation of IL-1ß and IL-6 in cardiomyocytes
Yoshimura et al., J Biol Chem 2011 : Mct-1 knockdown also prevented IL-1ß induced expression of phagocyte-type NADPH oxidase ( NOX-2 ), an enzyme specialized for production of ROS, whereas it did not have an effect on inducible NO synthase
Donini et al., Prostate 2012 (Prostatic Neoplasms) : LNCaP enhance IL-1ß , IL-23, IL-6, and TNF-a secretion by decreasing glucan dependent NADPH oxidase activity, whereas glucan increases IL-12 production through NADPH oxidase unrelated mechanisms
Bayat et al., Free Radic Biol Med 2012 : In conclusion, activation of TPr enhances IL-1ß induced Nox1 expression in VSMCs, which is responsible for the up-regulation of monocyte adhesion
Pang et al., Journal of neuroinflammation 2012 (MAP Kinase Signaling System) : Telmisartan reduced the IL-1ß induced increase in IL-1R1 receptor and NADPH oxidase-4 (NOX-4) mRNA expression, NADPH oxidase activity, and ROS generation, and reduced hydrogen peroxide induced COX-2 gene expression
Kanno et al., Am J Physiol 1994 : Among several cytokines and bacterial lipopolysaccharide tested, IL-1 beta most effectively stimulated NOx production