Gene interactions and pathways from curated databases and text-mining

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IL1A — LTA

Text-mined interactions from Literome

Hermann et al., Eur J Immunol 2002 : All LTA induced the release of TNF-alpha, IL-1beta , IL-6 and IL-10 in human whole blood
Bougarn et al., Clinical and vaccine immunology : CVI 2010 (Mastitis, Bovine...) : Although the levels of expression of the inflammatory cytokines tumor necrosis factor alpha ( TNF-a ) and IL-1ß were increased by LTA and MDP at the mRNA level, no protein could be detected in the bMEpC culture supernatant
Declue et al., Vet J 2012 (Inflammation) : LPS, LTA and PG stimulated tumor necrosis factor (TNF) and interleukin (IL)-6 production but only LTA and PG stimulated IL-1ß production from whole blood
Kaushansky et al., J Immunol 1988 : Using Northern blot analysis to detect tissue levels of hematopoietic growth factor-specific transcripts, and specific biologic and immunologic assays to detect the presence of colony stimulating factors in the serum, we have found that TNF-alpha and TNF-beta induce the transcription and production of granulocyte-macrophage-CSF, macrophage-CSF, and IL-1
Lindemann et al., J Dent Res 1988 (Periodontitis) : Whereas whole Gram positive bacteria had no stimulatory effect on monocytes, LTA induced IL-1 and TNF production at a concentration range equivalent to that of the LPS
Locksley et al., J Immunol 1987 : Even at concentrations as high as 600 pM, only 3 U of IL-1/ml were recovered ; maximal IL-1 release ( 10 to 12 U/ml ) required up to 5 nM TNF-beta