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IL1A — KLF4

Text-mined interactions from Literome

Mori et al., Mol Cancer Res 2009 (Pancreatic Neoplasms) : Importantly, KLF5 was significantly up-regulated by interleukin (IL)-1beta or hypoxia
Liu et al., FEBS Lett 2012 : The results showed LPS treatment resulted in the increase of KLF4 level and IL-1ß release ; KLF4 overexpression decreased the expression of IL-1ß, while KLF4 inhibition increased the expression of IL-1ß ; overexpression of KLF4 promoted the DNA binding activity of KLF4 to the IL-1ß promoter and attenuated the transcription of IL-1ß promoter, indicating an important role of KLF4 in regulating expression of IL-1ß