Gene interactions and pathways from curated databases and text-mining

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HSD11B1 — IL1A

Text-mined interactions from Literome

Rae et al., J Clin Endocrinol Metab 2004 : Progesterone also suppressed IL1alpha induced COX-2 mRNA expression but had no significant effect on IL1alpha stimulated 11betaHSD1 expression
Gubbay et al., Br J Cancer 2005 (Adenocarcinoma...) : In this study we directly compared levels of IL-1alpha induced gene expression by analysing the levels of 11beta-hydroxysteroid dehydrogenase ( 11betaHSD ) types 1 ( 11betaHSD-1 ) and 2 ( 11betaHSD-2 ), cyclooxygenase-2 (COX-2), IL-1 receptor (IL-1R) and glucocorticoid receptor alpha ( GRalpha ) mRNA between normal HOSE cells and cell lines derived from poorly differentiated ( SKOV-3, BG-1, PEO-4 ) and well differentiated ( PEO-14 ) ovarian adenocarcinoma
Fegan et al., J Endocrinol 2008 : IL-1alpha ( 0.5 ng/ml ) stimulated 11betaHSD1 and COX-2 mRNA levels in PSE cells but 11betaHSD2 was unaffected