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GRAP2 — IL18

Text-mined interactions from Literome

Ling et al., Crit Care Med 2002 : In contrast to its effects on the janus kinase/STAT pathways, interleukin-6 activation of MAP kinases ( extracellular signal regulated kinase-1, extracellular signal regulated kinase-2, and p38 ) was unaffected by endotoxin
Yan et al., J Biol Chem 2002 : This model probiotic also inhibits activation of the pro-apoptotic p38/mitogen activated protein kinase by tumor necrosis factor, interleukin-1alpha , or gamma-interferon
Sekiyama et al., Immunity 2005 : Inhibitors of caspase-1, reactive oxygen species, and P38 mitogen activated protein kinase ( MAPK ) suppressed stress induced accumulation of plasma IL-18
Niyonsaba et al., J Immunol 2005 (MAP Kinase Signaling System) : The human beta-defensins ( -1, -2, -3, -4 ) and cathelicidin LL-37 induce IL-18 secretion through p38 and ERK MAPK activation in primary human keratinocytes
Hewins et al., Kidney Int 2006 (Autoimmune Diseases...) : Furthermore, TNFalpha and IL-18 phosphorylated neutrophil p38 mitogen activated protein kinase ( MAPK ), but IL-18 mediated p38 MAPK phosphorylation was unaffected by anti-TNFalpha antibody
Rasheed et al., Arthritis Res Ther 2010 (Osteoarthritis) : Pomegranate extract inhibits the interleukin-1ß induced activation of MKK-3, p38a-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes