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AR — ERBB2

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: AR → Complex of ERBB2-ERBB3 (increases, ERBB2/ERBB3 Activity) Mellinghoff et al., Cancer Cell 2004*
  Evidence: This HER2/ERBB3 signal stabilizes AR protein levels and optimizes binding of AR to promoter/enhancer regions of androgen-regulated genes.

Text-mined interactions from Literome

Qin et al., Mol Cancer Res 2007 (Prostatic Neoplasms) : Wwox suppresses prostate cancer cell growth through modulation of ErbB2 mediated androgen receptor signaling
Zhang et al., Mol Cancer Ther 2008 (Disease Models, Animal...) : Aberrant activation of the androgen receptor (AR) by the ErbB2/ErbB3 heterodimer contributes to the development of hormone resistance in prostate cancer
Pignon et al., Cancer Res 2009 (Prostatic Neoplasms) : Androgen receptor controls EGFR and ERBB2 gene expression at different levels in prostate cancer cell lines
Cai et al., Cancer Res 2009 (Prostatic Neoplasms) : Androgen receptor expression in prostate cancer cells is suppressed by activation of epidermal growth factor receptor and ErbB2