◀ Back to ANGPT2
ANGPT2 — NCF1
Text-mined interactions from Literome
Touyz et al., Circ Res 2002
:
Ang II regulates the enzyme by inducing phosphorylation of
p47phox , translocation of cytosolic subunits, and de novo protein synthesis
Touyz et al., Arterioscler Thromb Vasc Biol 2005
:
The
p47phox : actin interaction, through cortactin,
plays an important role in
Ang II-mediated site directed assembly of functionally active NAD ( P ) H oxidase, ROS generation, and activation of redox-sensitive p38MAP kinase and Akt, but not ERK1/2
Touyz et al., Can J Physiol Pharmacol 2005
:
In addition,
Ang II promotes interaction between actin and
p47phox
Papparella et al., J Hypertens 2005
(Hypertension...) :
Ang II ( 1 micromol/l )
induced a larger
p47phox subunit translocation and increased intracellular O2 production to a larger extent in HT in comparison to NT and this effect was blocked by apocynin, an inhibitor of the NAD ( P ) H oxidase
Fujii et al., J Biol Chem 2005
:
Ang II-induced NFAT activation was
suppressed by diphenyleneiodonium ( an NADPH oxidase inhibitor ), dominant negative ( DN ) -Rac,
DN-p47(phox) , and an inhibitor of Galpha(12/13) ( Galpha(12/13)-specific regulator of G protein signaling domain of p115RhoGEF, p115-regulator of G protein signaling (RGS) )
Ding et al., American journal of physiology. Renal physiology 2007
:
ANG II induced translocation of
p47(phox) and p67(phox) from the cytosol to the membrane
Ahn et al., The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2010
:
Ang II increased the expression levels of
p47(phox) , p67(phox), and p22(phox), but EGCG counteracted this effect on p47(phox)