Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — NCF1

Text-mined interactions from Literome

Touyz et al., Circ Res 2002 : Ang II regulates the enzyme by inducing phosphorylation of p47phox , translocation of cytosolic subunits, and de novo protein synthesis
Touyz et al., Arterioscler Thromb Vasc Biol 2005 : The p47phox : actin interaction, through cortactin, plays an important role in Ang II-mediated site directed assembly of functionally active NAD ( P ) H oxidase, ROS generation, and activation of redox-sensitive p38MAP kinase and Akt, but not ERK1/2
Touyz et al., Can J Physiol Pharmacol 2005 : In addition, Ang II promotes interaction between actin and p47phox
Papparella et al., J Hypertens 2005 (Hypertension...) : Ang II ( 1 micromol/l ) induced a larger p47phox subunit translocation and increased intracellular O2 production to a larger extent in HT in comparison to NT and this effect was blocked by apocynin, an inhibitor of the NAD ( P ) H oxidase
Fujii et al., J Biol Chem 2005 : Ang II-induced NFAT activation was suppressed by diphenyleneiodonium ( an NADPH oxidase inhibitor ), dominant negative ( DN ) -Rac, DN-p47(phox) , and an inhibitor of Galpha(12/13) ( Galpha(12/13)-specific regulator of G protein signaling domain of p115RhoGEF, p115-regulator of G protein signaling (RGS) )
Ding et al., American journal of physiology. Renal physiology 2007 : ANG II induced translocation of p47(phox) and p67(phox) from the cytosol to the membrane
Ahn et al., The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2010 : Ang II increased the expression levels of p47(phox) , p67(phox), and p22(phox), but EGCG counteracted this effect on p47(phox)