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ANGPT2 — MIF
Text-mined interactions from Literome
Busche et al., Endocrinology 2001
:
Taken together with our observation that
MIF is expressed in the terminal fields of noradrenergic neurons ( hypothalamus ) and that
Ang II increases the expression of MIF in this region in vivo, our data may suggest a novel role of Ang II in norepinephrine metabolism
Rice et al., Kidney Int 2003
:
To determine whether
Ang II had a direct effect on
MIF production, mRNA synthesis and protein secretion were examined in proximal tubular epithelial ( NRK52E and MCT ) cell lines ... In vitro studies of tubular epithelial cells revealed that
Ang II caused a twofold increase in
MIF mRNA expression in NRK52E and MCT cells, which was abrogated by irbesartan
Zhong et al., Br J Pharmacol 2008
(Insulin Resistance) :
Gene transfer of ACE2 suppressed the expression of p22phox and
MIF induced by
angiotensin (Ang) II and Ang IV, accompanied by a decreased level of malondialdehyde in cells