Gene interactions and pathways from curated databases and text-mining

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ANG — SRC

Text-mined interactions from Literome

Espiritu et al., American journal of physiology. Renal physiology 2002 (Acidosis) : Regulation of renal Na-HCO cotransporter ( NBC1 ) activity by cholinergic agonists, ANG II, and acute acidosis ( CO ( 2 ) ) requires both Src family kinase (SFK) and classic MAPK pathway activation
Kyaw et al., Mol Pharmacol 2004 : Here we demonstrated that Ang II rapidly and significantly stimulated tyrosine phosphorylation of Src and Cas and their association in rat aortic smooth muscle cells ( RASMC )
Che et al., American journal of physiology. Renal physiology 2005 : The effect of Src kinase inhibition on ANG II-induced intracellular free Ca ( 2+ ) concentration ( [ Ca ( 2+ ) ] ( i ) ) responses was probed in fura 2-loaded preglomerular microvascular smooth muscle cells ( PVSMCs ) obtained from explants and studied after 3-5 days in culture
Macconi et al., Am J Pathol 2006 : Podocyte dysfunction was mediated by Ang II type 1 receptor and was partly dependent on Src kinase-phospholipase C activation
Kanda et al., Cell Signal 2007 : PP2 inhibited both Ang1 induced capillary morphogenesis and Src activation in HUVECs cultured under normoxic conditions, but the PP2 activity was significantly impaired in HUVECs cultured under hypoxic conditions
Jackson et al., J Cardiovasc Pharmacol 2007 : Because angiotensin II (Ang II) activates PLC and Src , and because PLC and Src inhibit and augment cAMP production, respectively, it is conceivable that the balance between these signal-transduction pathways determines whether Ang II increases or decreases cAMP production in SHR PGSMCs
Li et al., Am J Physiol Cell Physiol 2007 (MAP Kinase Signaling System) : The present study was designed to investigate the pathway by which ANG II activates Src leading to an increase in ERK1/ERK2 phosphorylation and an increase in NOS protein in PAECs
Sampaio et al., Hypertension 2007 : We also show that SHP-2-c-Src interaction is enhanced by Ang- ( 1-7 )