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ANG — PRKAR1B
Text-mined interactions from Literome
Shimoni et al., Am J Physiol Heart Circ Physiol 2004
(Diabetes Mellitus, Experimental...) :
ANG II
affects multiple cellular pathways including activation of protein kinase C ( PKC ) and several tyrosine kinases as well as inhibition of
protein kinase A (PKA)
Hubbard et al., Cell Immunol 2005
:
Cyclic AMP dependent protein kinase (PKA) played a major role in this enhancement since the
PKA inhibitor, H89,
blocked secretion of
Ang2
Lara et al., Arch Biochem Biophys 2010
:
Cholera toxin, an activator of Gs protein, mimicked it ; ( 2 ) in the presence of Ang II,
Ang- ( 1-7 )
increased the
PKA activity 10-fold ; ( 3 ) the peptide inhibitor of PKA blocked the Ang- ( 1-7 ) effect on Ang II-stimulated Na+-ATPase ; ( 4 ) Ang- ( 1-7 ) reverses the Ang II-stimulated PKC activity ; ( 5 ) cAMP mimicked the Ang- ( 1-7 ) effect on the Ang II-stimulated Na+-ATPase
Saraiva et al., PloS one 2011
(Malaria, Falciparum) :
These results indicate that the
effect of
Ang- ( 1-7 ) on P. falciparum blood stage involves a MAS mediated
PKA inhibition