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NOS3 — SCARB1

Text-mined interactions from Literome

Li et al., J Biol Chem 2002 : In the present studies we used a Chinese hamster ovary cell system and a human microvascular endothelial cell line to confirm that HDL stimulates eNOS activity in a SR-BI dependent manner
Gong et al., J Clin Invest 2003 : Studies with ovariectomized and ovariectomized/estrogen replacement mouse models demonstrated that HDL associated estradiol stimulation of eNOS is SR-BI dependent
Mineo et al., Trends Cardiovasc Med 2003 : Recent work in both cell culture and in mice indicates that HDL causes robust activation of endothelial nitric oxide synthase (eNOS) , and that this effect is mediated in endothelial cell caveolae by SR-BI through a process that requires apoA-I binding
Assanasen et al., J Clin Invest 2005 : In addition, eNOS activation by methyl-beta-cyclodextrin was SR-BI dependent
Mineo et al., Curr Opin Lipidol 2012 (Atherosclerosis...) : In endothelial cells, SR-BI mediates HDL induced endothelial nitric oxide synthase activation and proliferation and migration, and in platelets SR-BI may be prothrombotic in the setting of dyslipidemia