Gene interactions and pathways from curated databases and text-mining

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NOS3 — RETN

Text-mined interactions from Literome

Kougias et al., J Vasc Surg 2005 : In this study, we determined whether resistin could affect vasomotor function, oxidative stress, and endothelial nitric oxide synthase (eNOS) expression in porcine coronary arteries ... This study showed that resistin can cause endothelial dysfunction in porcine coronary arteries through oxidative stress and down-regulation of eNOS
Shen et al., J Biol Chem 2006 (Cardiovascular Diseases...) : In the current study, we observed that resistin inhibited insulin signaling and eNOS activation in endothelial cells ... In summary, up-regulation of PTEN is involved in the inhibitory effects of resistin on insulin signaling and eNOS activation in endothelial cells ... Our findings suggest that resistin mediated inhibition of insulin signaling and eNOS activation may contribute to cardiovascular diseases
Chen et al., Am J Physiol Heart Circ Physiol 2010 (Atherosclerosis) : Three antioxidants, seleno-L-methionine, ginsenoside Rb1, and MnTBAP ( superoxide dismutase mimetic ), effectively blocked resistin induced eNOS downregulation