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IL8 — MET
Text-mined interactions from Literome
Cosentino et al., Int Immunopharmacol 2010
:
In human PMNs, HMR concentration-dependently reduced ROS production induced by either N-formyl-Met-Leu-Phe, phorbol myristate acetate or angiotensin II, as well as
interleukin-8 production
induced by either
N-formyl-Met-Leu-Phe or angiotensin II
Hill et al., PloS one 2012
(Cell Transformation, Neoplastic...) :
Met receptor tyrosine kinase signaling
induces secretion of the angiogenic chemokine
interleukin-8/CXCL8 in pancreatic cancer ... Notably, we report that
Met signaling
regulates the secretion of the pro-angiogenic chemokine
interleukin-8/CXCL8 ... Our data showing that the interleukin-8 receptors CXCR1 and CXCR2 are not expressed on pancreatic tumor cells, suggests a paracrine mechanism by which
Met signaling
regulates interleukin-8 secretion to remodel the tumor microenvironment, a novel finding that could have important clinical implications for improving the effectiveness of treatments for pancreatic cancer
Proudfoot et al., J Biol Chem 1996
:
The antagonistic effect was selective since
Met-RANTES had no effect on
interleukin-8- or monocyte chemotractant protein-1 induced responses in these cells